范盛華教授學術專題演講106/12/11

  • 2017-12-04
  • 楊 文敏

國立政治大學統計學系
     
主講人:范盛華 教授
                          Dept. of Statistics and Biostatistics
                 California State University at East Bay
    目:Curve-free Bayesian Decision-theoretic Designs for Dose-finding Phase I Trials
    間:民國1061211 (星期一) 下午1330
    點:政治大學逸仙樓050101教室
    要:
              Although Bayesian statistical methods gain attention in the medical community, as they provide a framework for incorporating prior information, the complexity of these methods limited their adoptions in real trials. In addition, how to set up prior distributions is often mysterious to clinicians even to biostatisticians. In this talk, we will propose a curve-free Bayesian method for dose-finding trials, which is easy to understand and implement, yet performs comparably to or better than many other more complex Bayesian methods. We will begin with the simplest case, one-agent case, then to two-agent case and finally to the trials with two responses (toxicity and efficacy).