范盛华教授学术专题演讲106/12/11

  • 2017-12-04
  • 杨 文敏

国立政治大学统计学系
     
主讲人:范盛华 教授
                          Dept. of Statistics and Biostatistics
                 California State University at East Bay
    目:Curve-free Bayesian Decision-theoretic Designs for Dose-finding Phase I Trials
    间:民国1061211 (星期一) 下午1330
    点:政治大学逸仙楼050101教室
    要:
              Although Bayesian statistical methods gain attention in the medical community, as they provide a framework for incorporating prior information, the complexity of these methods limited their adoptions in real trials. In addition, how to set up prior distributions is often mysterious to clinicians even to biostatisticians. In this talk, we will propose a curve-free Bayesian method for dose-finding trials, which is easy to understand and implement, yet performs comparably to or better than many other more complex Bayesian methods. We will begin with the simplest case, one-agent case, then to two-agent case and finally to the trials with two responses (toxicity and efficacy).